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The mechanisms underlying mitochondrial dysfunction include excessive generation of mitochondrial ROS (mtROS), loss of mitochondrial membrane potential, release of (mtDNA into the cytoplasm, and dysregulation of mitochondrial dynamics such as fission and fusion (Monzel et al., 2023)

The patient profile that benefits most from combining both therapies fits what we call the anti-aging aesthetics track at Perfect B: GHK-Cu for tissue repair and hair, NAD+ for cellular energy and longevity

Even tiny amounts of condensation can initiate hydrolysis, breaking down the peptide bonds

Further studies also suggest that the amino-acid sequence of GHK-Cu may have an antioxidative potential on ROS, such as hydroxyl radicals, and it may be even stronger than generic antioxidative peptides