In response to its potential hazards, several regulatory strategies have been proposed, including promoting the recovery of butyrate-producing bacteria, such as Faecalibacterium , to competitively inhibit its proliferation and optimizing the gut microbiome structure through probiotic supplementation and dietary fiber interventions 142
However, the greatest weight loss and abdominal fat reduction, which was measured by dual X-ray absorptiometry, were seen in GLP-1RAs combined with sodium-glucose cotransporter-2 inhibitors (SGLT2i) and phentermine topiramate
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It plays a critical role in maintaining cellular health by neutralizing free radicals and reactive oxygen species, which can cause oxidative stress and damage to cells