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Interestingly, it has been shown in trials that GLP-1 inhibitors increase alcohol consumption, and GLP-1 receptor agonists reduce alcohol consumption in patients with type-2 diabetes mellitus

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Data from the SURPASS-PEDS trials, which was simultaneously published in The Lancet , showed once-weekly subcutaneous tirzepatide (Mounjaro, Eli Lilly), a GIP/GLP-1 dual agonist, conferred significant reductions in both HbA1c and BMI at 30 weeks compared with placebo