This approach has already been incorporated into radiotoxicity prediction through single nucleotide polymorphism-based models [77]
Regnier, M., Vega, C., Ioannou, D
However, attempts to measure MTOB and homomethionine transport activity of recombinant BAT5 in vitro were not successful till now, as the direct measurements of transport of these substrates in artificial membranes is problematic due to higher hydrophobicity of substrates leading to unspecific membrane binding and permeation, which override the specific transport events ( PAPS/PAP ANTIPORTER IN CHLOROPLASTS Along with the BAT5, which exchanges 2-keto acids between chloroplast and the cytoplasm, the chloroplastidic transporter of activated sulfate (PAPS), which is essential for the sulfation of GSLs, flavonols, peptides, and other sulfated compounds in the cytoplasm has been recently identified ( Figures 1 and 2 , transporter 5)
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Eur J Orthop Surg Traumatol 34 , 9196 (2024)