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[Figure 4](b) Examples of synthetic, pharmaceutically important substituted amphetamines

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Because it spreads fast, it may not be diagnosed until it has already spread

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Notably, these GABA-A receptor subunit genes are clustered on chromosome 15q12, forming a gene cluster comprising GABRB3, GABRA5, and GABRG3

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doi: 10.4093/dmj.2020.0258 38 United States Food and Drug AdministrationCenter for Drug Evaluation and Research

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