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According to NICE guidance (NG28), the continuation of GLP-1 receptor agonist therapy in type 2 diabetes should be assessed after six months, with treatment continued only if there is a reduction in HbA1c of at least 11 mmol/mol (1%) and, where applicable, a weight loss of at least 3% of initial body weight

Injection reactions are common and can include redness, irritation, or mild flu-like symptoms

Of course, that doesn't mean we still can't have fun with makeup (the gram still exists after all)

Cristofano et al., 2016

Common reports include localized irritation at the injection site, mild fluid retention with CJC-1295/Ipamorelin, and rare allergic-type reactions