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Treatment should be discontinued if the glycemic response is inadequate, side-effects are intolerable, other treatments in development prove more effective, and according to patient preference

no completed large-scale human efficacy trials for muscle, recovery or anti-aging

Semaglutide, for example, has been shown in trials to cut the risk of cardiovascular problems such as heart attack and stroke in people who are overweight or have obesity, and to cut the risk of complications from kidney disease in people with Type 2 diabetes

It does not set a fixed time limit for how long a person should take the medication

MotherToBaby notes that transfer into breast milk is unlikely but recommends caution, especially for newborns and preterm infants