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And now Indiana has become a center of not just the thought but also the manufacture of medications that are proving to be some of the most life-changing medical treatments weve ever seen. IU has long been home to remarkable discoveries in chemistry like DiMarchis, including the invention of the key ingredient in Crest toothpaste

13 However, the clinical relevance of these mechanistic advantages in adolescent populations remains uncertain due to the absence of robust pediatric data

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FERM domain (Protein 4.1, ezrin, radixin and moesin domain)