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BioFactors 39 (1), 3755

Disrupting MYSM1 (Myb like, SWIRM and MPN domains 1), a histone deubiquitinase, can compromise human HSC function, mimicking the bone marrow failure seen in patients, by triggering lipid peroxidation and ferroptosis [203]

Additionally, a digital elevation model will be utilized to assess walkability

381 Surprisingly, statins can decrease the levels of mevalonate-5-phosphate and prevent mutated p53 from binding to HSPs, thus promoting the degradation of structural p53 mutants by MDM2 or CHIP E3

Protection of the cardiovascular system Inhibition of cholesterol synthesis Garlic and garlic-derived organosulfur compounds have been found to decrease the synthesis of cholesterol by hepatocytes (38)