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There is a pattern of relapse after stopping other therapies

Ngounou Wetie, A.G., et al

For scientists and clinicians, its an excellent candidate for further study

Lactate metabolism and histone lactylation in the central nervous system disorders: impacts and molecular mechanisms

low T3/T4 reduces their activity *Elevated homocysteine - hypothyroidism raises homocysteine levels, which depletes glutathione and increases cardiovascular oxidative stress A study on thiol-disulfide and glutathione homeostasis in thyroid patients found that "oxidative stress remains a prevailing issue in patients with autoimmune or non-autoimmune hypothyroidism" - confirming that glutathione depletion is a consistent feature across the thyroid disease spectrum, not limited to autoimmune forms