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Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase

A., Fletcher, M., Hollinghurst, S., & Peters, T

Density for the remaining D2b domain residues 774798 and 886990 (forming a four-helix structure capped by a two-stranded -sheet) only appears at lower thresholds in the cryo-EM map, indicating that this domain is more flexible (Supplementary Fig

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Although this unifying perspective may require more data to confirm, it shows the complexity of progesterone biology